ABSTRACT

Background: Diabetic mellitus jaundice, and cardiovascular problems are the leading causes of death in both developed and developing countries. Preterm newborns with higher levels of cord blood glucose, total cholesterol, triglyceride, LDL, and VLDL may have a higher future risk of cardiovascular disease in diabetes mellitus. Early detection, dietary changes, and adequate management may be able to correct risk factors and avoid disease in the future. The goal of this study is to do biochemical profiling in preterm and full-term neonates' umbilical cord blood. Methods: It is retrospective and observational study conducted for a period of two years from October 2018 to November 2020 in the Departments of Biochemistry and Gynecology of Santosh Medical College and Hospitals, Ghaziabad and K. D Medical College and Research center Mathura. Results: Umbilical Cord blood serum blood sugar, total cholesterol, triglyceride, LDL, and VLDL were higher in preterm babies compared to term babies in a study of 200 neonates, with 100 (50 percent) term and 100 (50 percent) preterm babies. Baby weight was also significantly increased (<0.05) in term babies compared to preterm babies. Conclusion: There is an inverse association between gestational age and several biochemical markers, and the preterm group's abnormal biochemical profile may be a risk factor for the development of diabetes and cardiovascular disease later in life. Keywords: Newborn, Preterm neonates, Umbilical cord blood study, Low birth weight
Publication date: 01/12/2021

https://ijbpas.com/pdf/2021/December/MS_IJBPAS_2021_DEC_SPCL_2029.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.12.2029