ABSTRACT

This article illustrates the importance and implementation of green chemistry practices in the pharma industry. The current climate interrelated to impending Global crises shows the impact on green chemistry, which provides unique opportunities for innovations via product substitution, new feedstock generation, catalysis in aqueous media, utilization of microwaves, the scope for alternatives, or natural solvents. This paper summarizes the environmental protocols for the synthesis of some FDA-approved drugs which possess high volume demand coupled with their requirement of high chemical and optical purity, utilization of green chemistry. Various innovations in green chemistry such as the use of catalysts in experiments, safer chemicals and auxiliaries, design for degradation with the more efficient synthetic formulation. This conceptual paper demonstrates how the principles and metrics influence the life cycle chemicals from design to disposal and steps taken for sustainability development. It is driven by a desire to reduce costs and increase the sustainability of the manufacturing process. The Regulatory restrictions and self-impositions in adopting green chemistry by this pharmaceutical industry have made a significant impact. The concept in the new act was to adopt a process that generates no pollutants rather than treating pollutants after products. It states that the cost-effective modernization of the regulatory process will protect human health and the environment while also reducing the burden to the industry. This article defines how pharmaceutical manufacturers change methods into "greener methods to use less toxic reagents and solvents to minimize their effluents and solid waste. Green chemistry is not just a catchphrase. It is an essential principle of chemical research that will sustain our society in the 21st century and further into the future. This core concept described a research success from the last 20 years, including advances in synthetic efficiency application, of alternative synthetic methods, use of less hazardous solvents and Reagents, and development of renewable feedstock. Further green chemistry will depend on innovations that consolidate and integrate these achievements made using principles as a framework for design for sustainability and reduce hazards should be eliminated as contrasting but provide freedom to explore and invent scientific disciplines to create new solutions. Keywords: Green chemistry, sustainability, alternative assessment, harmful chemicals
Publication date: 01/12/2021

https://ijbpas.com/pdf/2021/December/MS_IJBPAS_2021_DEC_SPCL_2011.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.12.2011