ABSTRACT

Recently the use of herbal medicines has increased all over the world due to their miraculous therapeutic effect and better safety profile. However, the delivery of drugs of natural origin may require modifications with the objective to achieve improved efficacy, to increase patient compliance, improved stability etc. Previously drugs of natural origin were not considered as agent to develop novel drug delivery system due to processing, standardizing, extracting and identification difficulties. But now a days with the advancement in formulation development, novel formulation technologies open the door towards the drugs of natural origin. This combination may result in the creation of new segment in health care. The present study aims to prepare a suspension which is a value-added formulation of Kamadhugha Rasa, a classical Ayurvedic formulation. The final product Kamadhugha Rasaisin powder form as per the classical references and it has to be administered to the patients along with the vehicles like ghee, honey etc. Soin order to make the formulation more user friendly it has been modified into a liquid dosage form. The liquid dosage form may provide better patient compliance for those with swallowing difficulties. There are potential advantages of oral liquid dosage forms, such as no dissolution time and rapid absorption from the stomach/intestines compared to solid dosage form. Considering these literary facts, liquid dosage form suspension was selected. Thus, sticking on to the basic principles by Acharya value addition was done in classical Kamadhugha Rasa form. While preparing suspension, instead of water amalaki swarasa was used. Artificial sucrose was replaced by sugar mentioned as adjuvant in the formulation. The suspension was preserved by adding honey, a natural preservative. In addition to honey, Vitamin C in Amalaki also serves as a preservative. Thus, through the current study, a value- added suspension of Ayurvedic classical formulation Kamadhugha Rasa was developed and the analytical parameters were evaluated. Key words: Kamadhugha Rasa, Suspension, Value addition, Liquid dosage form
Publication date: 15/12/2021

https://ijbpas.com/pdf/2021/December/MS_IJBPAS_2021_DEC_SPCL_1053.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.12.1053