ABSTRACT

Standardization in medical practice is a system which ensures that every packet of medicine that is sold maintains the quality and quantity of the requisite bioactive compound and will induce the desired therapeutic effect. The most important step with respect to standardization of herbal drugs is the correct taxonomic identification of the concerned species, whether in fresh, dried or powdered state. The plant selected for the present investigation is Tridax procumbens L., belonging to the family Asteraceae. The plant originated in Central America but now occurs throughout the tropics and subtropics. A morphological study of the plant was conducted. The whole plant was shade dried and ground to fine powder and subjected to organoleptic, fluorescent and physicochemical analysis. The plant powder was subjected to Soxhlet extraction using methanol as the solvent. Phytochemical screening (Qualitative and Quantitative) of the plant extract was done according to the standard biochemical procedures. Antioxidant activity of the plant extract was tested using ABTS assay. The organoleptic analysis revealed characteristic colour, taste, odour and nature of the powder of Tridax procumbens. In fluorescence analysis, on treatment with different solvents, colour changes could be noticed in the plant powder. The results of the physicochemical analysis provided important parameters in detecting adulteration or improper handling of drugs. Qualitative and quantitative analysis in the plant confirmed the presence of many important phytochemicals such as tannins, saponins, flavonoids, terpenoids, alkaloids, simple phenolics, coumarins, quinones, acids, lignin and flavanols. Bioactivity study indicated that the antioxidant potential of the plant is comparable to that of the standard Trolox. The present work will be useful in the synthesis of new drugs of pharmaceutical importance from Tridax procumbens. Keywords: Tridax procumbens, Asteraceae, Organoleptic, Phytochemical, antioxidant
Publication date: 15/12/2021

https://ijbpas.com/pdf/2021/December/MS_IJBPAS_2021_DEC_SPCL_1036.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.12.1036