ABSTRACT

Celastrus paniculatus Willd. (Cp) from North-Western Himalayas (Family: Celastraceae) is a traditional established Ayurvedic herb. The usage of Cp in medicine dates back to ancient times and also appears in Ayurveda. An investigation is being conducted to find out whether whole plant of Cp (apart from roots) from north-western Himalayas (Himachal Pradesh) can be used for treating neurosarcoidosis in the future. Successive solvent extraction was performed with acetone, chloroform, ethanol and water. Further, in vitro antioxidant assessment has been performed which includes Hydroxyl radical (HO·) scavenging, ABTS radical decolorization assay, H2O2 scavenging activity, DPPH radical reducing activity, superoxide radical (O2•–) scavenging activity, metal chelating activity, NO· scavenging activity, hydroxyl radical (HO·) scavenging and reducing power assay. By the examination of IC50 (Half maximal inhibitory concentration) value from the in vitro antioxidant data of each extract it has been observed that the water extract has the remarkable antioxidant potential. The potency of all the extracts in terms of IC50 follows the orders as CpW Publication date: 15/12/2021

https://ijbpas.com/pdf/2021/December/MS_IJBPAS_2021_DEC_SPCL_1012.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.12.1012