ABSTRACT

Erectile dysfunction (ED) is a major health problem affecting 52% of men between 40 and 70 years. The association between ED and hypercholesterolaemia has also been studied extensively. Combination drug products occupy a time-honored and important role in therapeutics. The combination of Atorvastatin Calcium and Sildenafil is commercially available in tablet form to control erectile dysfunction. The Atorvastatin calcium and Sildenafil co- formulation, the IIEF-5 score was significantly decreased, maintaining cholesterol level. Analysis of samples with numerous components presents a major challenge in modern analysis. This article narrates different chromatographic (HPLC, HPTLC, UPLC, LC) & different spectrophotometric method (UV) for determination of the Atorvastatin Calcium and Sildenafil single drug as well as combination with other drug. Keywords: Estimation, Atorvastatin Calcium, Sildenafil, UV Spectroscopy, RP HPLC
Publication date: 01/12/2021

https://ijbpas.com/pdf/2021/December/MS_IJBPAS_2021_5767.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2021/10.12.5767