ABSTRACT

4-methylphenol based compound, 2-(1,3-dithiolan-2-yl)-6-(hydroxymethyl)-4-methylphenol (L2) was designed, synthesised and characterised using x-ray single crystallographic tools. The tittles compound was synthesized via two steps where the first step involves the formation of mono-blocked compound, L1. L1 compound was initially synthesized by blocking of one aldehyde group out of two symmetrically positioned aldehyde group of 2,6-diformyl-4-methylphenol. The second step involves the mild reduction of unblocked-aldehyde group using NaBH4. This process involved interesting synthetic methodology. X-ray single crystal data were collected using Mo-Ka (? = 0.7107 Å) radiation on a SMART APEX II diffractometer equipped with CCD area detector. The tittles compound, L2 crystallises in monoclinic crystal system with P 21/c space group when allowed to evaporate the desired organic solvent. Keywords: X-ray single crystallography, 4-methylphenol, reduction, NaBH4
Publication date: 01/12/2021

https://ijbpas.com/pdf/2021/December/MS_IJBPAS_2021_5754.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.12.5754