ABSTRACT

Glibenclamide belongs to the class second generation sulfonyl ureas used in the management of diabetes. The present review is generalized to describe the various methods of UV, HPLC, HPTLC, UPLC and UHPLC for glibenclamide analysis in formulations, synthetic mixtures and biological fluids. The chromatographic conditions used for the analysis were performed under various experimental conditions and combinations. Analytical parameters such as wavelength, solvent, mobile phase, correlation coefficient, linearity, retention time, retardation factor, LOD, LOQ and so on are written in this review. For budding researchers, this review is very helpful in the analysis of glibenclamide in formulation, biological fluids and synthetic mixtures. Keywords: Glibenclamide, Metformin Hydrochloride, Pioglitazone, Glimepiride, HPLC, chromatography, flow rate, retention time
Publication date: 01/12/2021

https://ijbpas.com/pdf/2021/December/MS_IJBPAS_2021_5746.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.12.5746