A STUDY IN MICROBIOLOGICAL PROFILE OF SURGICAL SITE INFECTION IN POST-SPLIT SKIN GRAFT PATIENTS WITH TYPE II DIABETES MELLITUS
Authors: Hubert Cyril Lourdes* and Gawtham D

ABSTRACT
Background: Diabetic patients are immunocompromised and are most prone to develop Leg and Foot ulcers, which might grow bigger in size due to poor attendance of the wound / ulcer. These ulcers are then treated and aided in heal by secondary intention. During this process, if the raw area is more than 5x5cm, these raw area are prone for secondary infections, hence Split Skin Grafting is proposed and done. Diabetic patients are immunocompromised, due to which a variety of organisms grow under the Graft, which invades the wound and delays healing and spread to deeper tissues, resulting in Graft loss and reinfection of the healed ulcer. Materials and Methods: The key aim of this study is to identify the most common and prevalent organisms occurring in surgical site infection in Post SSG patient with Type II Diabetes Mellitus and to assess the sensitivity pattern of the antibiotics for controlling the infection.In this study, 63 patients presenting with Diabeticfoot / Leg ulcers to the Department of General Surgery, SBMCH were selected, treated and prepared for SSG, following which serial wound swabs were taken from the SSG site and studied. Results: Most common organisms were gram negative rods, gram positive cocci. Klebsiella pneumoniea and Klebsiella oxytoca were the most common gram negative organisms. Escherichia coli was the most common gram negative rod and Methicillin sensitive staphylococcus aureus was the most common gram positive cocci. Tobramycin, Piperacillin Tazobactam, Meropenem and third generation cephalosporins were the sensitive antibiotics. Conclusion: It has been concluded that strict glycemic control, appropriate pre-operative antibiotic prophylaxis, strict maintenance of chain of sterility and regular dressings under strict asepsis along with rational use of antibiotics to prevent the development of resistance and proper wound care. Keywords: Diabetes, immunocompromised, Klebsiella pneumoniea and Klebsiella oxytoca
Publication date: 01/11/2021
    https://ijbpas.com/pdf/2021/November/MS_IJBPAS_2021_57442.pdf
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https://doi.org/10.31032/IJBPAS/2021/10.11.57442