ABSTRACT

INTRODUCTION Systemic lupus erythematosus (SLE) is a multisystem, auto- immune disorder, characterized by the presence of multiple autoantibodies and deposition of immune complexes in various tissues [1]. Presentation 22-year-old lady known case of Hypothyroidism, presented in 2018 September with fever polyarthritis seizures and small vessel vasculitis on leg. She was evaluated and diagnosed as Systemic lupus erythematosus with hematological and neurological and vascular involvement Initial evaluation revealed pancytopenia with lymphopenia very low complements and positive ANA, dsDNA, Sm and ribosomal antibodies.Her direct coombs test was also positive. She was managed with mycophenolate mofetil and pulse steroids followed by tapering dose of steroids starting from 1mg/kg and hydroxy-chloroquine. She was maintaining clinical and laboratory based remission for 6 months.
Publication date: 01/11/2021

https://ijbpas.com/pdf/2021/November/MS_IJBPAS_2021_5742.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.11.5742