ABSTRACT

Background: Hypertension is one of the leading causes of morbidity, mortality as well as cost incurring treatment among cardiovascular diseases. Most antihypertensive drugs target different pathological and physiological response through different mechanism of action in order to keep the blood pressure within normal limit. Objective: The Objective of the study is to analyze the prescriptive pattern of antihypertensive drugs according to World Health Organization (WHO) drug use indicators in hypertensive outpatient clinic of a Tertiary care teaching hospital. A prospective cross-sectional study was conducted for 6 months in Hypertensive clinic, Sree Balaji Medical College Hospital. Patients of either sex ranging from 18-75 years who visit the OPD of hypertensive clinic were included in the study. Materials and Methods: (WHO) World Health Organization drug use indicators (core indicators and complementary indicators) were evaluated and defined daily dosage (DDD) were calculated in this study using the formula. Results: A total of 573 prescriptions were collected and the average number of drugs per prescription was 1.75. 60.02% of generics and 96.62% of essential drugs have been prescribed. Amlodipine is most prescribed among new hypertensive cases and Telmisartan and hydrochlorothiazide diuretics among chronic cases. The average consulting times were 9.78 min and dispensing time were 45.17 sec. The DDD/1000/day for ARB (Angiotensin receptor blocker) was the highest (312.86) and Propanolol was the lowest (25.32). Conclusion: It was concluded that the generic and essential drug prescription is high. Keywords: Antihypertensive prescription pattern, WHO indicators, DDD
Publication date: 01/11/2021

https://ijbpas.com/pdf/2021/November/MS_IJBPAS_2021_5741.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.11.5741