ABSTRACT

Objectives: To study the in vitro anti-diabetic and antioxidant activity of Barleria cristata in two extracts hexane and chloroform. Material and Methods: hexane and chloroform extract of leaf of Barleria cristata was tested for their anti-diabetic activity. The in vitro anti-diabetic activity from ?-amylase, ?-glucosidase and antioxidant activity was used to assess the potential activity of the fractions. Results: Our attempt results suggest that hexane and chloroform leaf extract from Barleria cristata show signs of dose-dependent increases to inhibitory activity on ?amylase, ?-glucosidase enzymes and antioxidant activity when compared with control. Hexane leaves to extract produced maximum in-vitro anti-diabetic effect and antioxidant activity when compared to chloroform extract. Conclusion: The Hexane leaf extract from Barleria cristata may be used in managing of blood glucose in medical condition like diabetes. Keywords: Barleria cristata; hexane extract; chloroform extract; anti-diabetic activity; antioxidant activity; in vitro study
Publication date: 01/11/2021

https://ijbpas.com/pdf/2021/November/MS_IJBPAS_2021_5733.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.11.5733