ABSTRACT

Human coronaviruses, first identified in the 1960s, are responsible in children for a large proportion of upper respiratory tract infections. At least five new human coronaviruses, including the extreme acute respiratory syndrome coronavirus, have been reported since 2003 and have caused substantial morbidity and mortality. NL63, representing the newly identified group I coronavirus group, which includes NL and New Haven coronavirus, has been identified worldwide. These viruses are associated with both upper and lower respiratory tract diseases and are probably common human pathogens. The global distribution of the newly identified HKU1 group II coronavirus has not yet been established. Coronavirus Disease (COVID?19) now dominates the lives of all, and its history is constantly being rewritten. This article gives a brief account of the story so far: where SARS?CoV?2 may have originated, how it compares with other viruses that cause major respiratory diseases, and some of the treatments and vaccines currently being studied to combat it. Here, the background and history of this important and expanding research area are reviewed. Key words: Coronavirus, NL63, HKU1, SARS-CoV-2, COVID-19
Publication date: 01/11/2021

https://ijbpas.com/pdf/2021/November/MS_IJBPAS_2021_5728.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.11.5728