ABSTRACT

Bacopa monnieri (BM) is a small, creeping, somewhat succulent herb. Bacopa is a member of the family Scrophulariaceae. Objective of this research work was to carry out comparative pharmacological studies of natural and micropropagated plants of Bacopa monnieri. The plant is cited for medicinal activity in Indian system as laxative, carminative, digestive, antiinflammatory, anti-convulsant, bronchodilator, febrifuge, and nervine tonic. It shows the presence of various phytoconstituents namely, alkaloids, saponins, phenolics and flavonoids in phytochemical screening. The tissue culture has been developed for regeneration of the BM plant from nodal segment. The regenerated plant having the similar potential in terms of phytoconstituents and antioxidant activity. The In vitro (leaf and stem) regenerated plants have slightly less antioxidant activity as compared to the In vivo but comparable. The pharmacological profile indicates that the micropropagated plant have the better activity namely Transfer latency and swim test than that of the naturally grown strain of B. Monnieri. Keywords: Bacopa monnieri, pharmacological studies, micropropagated plants, Brahmi, Motor activity, Transfer latency
Publication date: 01/11/2021

https://ijbpas.com/pdf/2021/November/MS_IJBPAS_2021_5706.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.11.5706