AN INSIGHT INTO THE ROLE OF VITAMIN D IN COVID-19: A REVIEW Authors: Mehta AA , BASU D AND MEHTA SA
ABSTRACT
Background: Coronavirus disease 2019 (COVID-19) is declared as global pandemic by the
World Health Organization, and a very few information is known about its treatment and
prevention. The novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus -2 (SARSCoV-2) a causative agent of COVID-19 is spreading rapidly, and it’s an issue of public health of
emergency worldwide. Epidemiological data have been reported that lower status of vitamin D
level may enhance COVID-19 mortality. Literature reviews showed the various
pathophysiological mechanism links between Vitamin D and COVID-19. Past reports suggest
that vitamin D supplementation may significantly decrease COVID-19 mortality effects and
boosts immunity to tackle this deadly virus. Aim: To reveal the role of vitamin D in COVID-19
and suggestion of vitamin D supplementation as a potential therapy in COVID-19. Methods: We
had performed a systematic review based on available literature of vitamin D in COVID-19
using PubMed, Google Scholar, and Willey online library databases up to August
2020. Conclusion: Based on available data we propose that vitamin D supplementation may play
a significant role in preventing COVID-19 mortality rate and/or also act as a prophylactic agent
for COVID-19. However, there is a need to generate clinical evidences or future trials to prove
the association between vitamin D and COVID-19.
Keywords: COVID-19, Vitamin D supplementation, Mortality rate, Prophylactic agent,
SARS-CoV-2, clinical evidences Publication date: 01/11/2021 https://ijbpas.com/pdf/2021/November/MS_IJBPAS_2021_5689.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2021/10.11.5689
