ABSTRACT

According to the BCS classification system class 2 drug have low solubility and high permeability. In the present study it was, planned to review the improved solubility of BCS class 2 drugs by preventing its dihydrate formation, by using co-crystal formation approach. It is widely accepted method to improve physical properties of BCS class 2 drug especially solubility.Co-crystal are prepared by using co-crystal former because it contains many hydroxyl groups and thus has potential to form hydrogen bonds with other components. Keywords: Co-crystal, co-former, solubility
Publication date: 01/10/2021

https://ijbpas.com/pdf/2021/October/MS_IJBPAS_2021_OCT_SPCL_1037.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.10.1037