IN VITRO ANTHELMINTIC ACTIVITY OF WATER AND ETHANOLIC EXTRACT OF STEM-BARK OF DOLICHONDRONE FALCATA (SEEM) Authors: Nitin B Aher , SANJAY RAVINDRA CHAUDHARI, ATUL A BARAVKAR AND JEEVAN S DHUMAL
ABSTRACT
Water and ethanolic extracts of Dolichondrone falcata (Seem) were evaluated for their
anthelmintic activity using Indian mature earthworm called Pheretima posthuma. Various
concentrations of water and ethanolic extract ranging from 10 to 100 mg/ml were made and
tested on said earthworm. The bioassays were tested for these extracts which include time for
paralysis and time for death of the worms. Water as well as ethanolic extract revealed good
anthelmintic activity at concentration of 100 mg/ml. Lower concentrations did not produced any
significant anthelmintic activity. The standard reference drug used is piperazine citrate at
concentration of 10 mg/ml for comparing anthelmintic activity of these extracts.
Keywords: Pheretima posthuma, Dolichondrone falcata (Seem), Extraction, Anthelmintic
activity, piperazine citrate etc. Publication date: 01/10/2021 https://ijbpas.com/pdf/2021/October/MS_IJBPAS_2021_OCT_SPCL_1028.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2021/10.10.1028