DEVELOPMENT AND EVALUATION OF HERBAL WHITENER SKIN FORMULATION USING TYROKINASE INHIBITION PROPERTY Authors: Dongawar R B , MAHAJAN U.N. AND THAKARE V.M.*
ABSTRACT
Background: Cosmetic products are used to protect skin against exogenous and endogenous
harmful agents and thereby enhance the beauty and attractiveness of skin. The products that
are used for skin brightening directly or indirectly inhibit the synthesis of melanin, which is
one of main cause of skin darkening.
Material & Methods: Herbal skin whitening topical formulation was prepared by using
some herbal extract. The different ratios of herbal constituents were tried with different
topical formulations. Formulations which was prepared by using Curcuma longa extract,
Mahua oil, Hibiscus sabdariffa extract and Cynodon dactylon extract using water in oil
emulsion base. Out of the prepared batches on trial and error basis, three formulation batches
showed appropriate and considerable results with marketed formulation.
Conclusion: The Flavonoids having ability as a skin whitening agent so total flavonoid
content was determined. The evaluation parameters was selected as preliminary
phytochemical tests, pH, viscosity, spreadability, total flavonoid contents, TLC, HPTLC,
FTIR, accelerated stability study which was within limit. The Curcuma longa extract, mahua
oil, hibiscus sabdariffa have the tyrokinase inhibition property, which reduces melanin
production.
Keywords: Curcuma longa, Madhuca indica, Hibiscus sabdariffa, Cynodon dactylon, skin
whitener Publication date: 01/10/2021 https://ijbpas.com/pdf/2021/October/MS_IJBPAS_2021_OCT_SPCL_1001.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2021/10.10.1001