ABSTRACT

The present study was undertaken to assess the effects of leaves extracts of Dypsis lutescens (H.Wendl.) and Caryota urens (L.) both belonging to the family Arecaceae on the blood sugar and lipid levels in diabetic rats. The Leaves of Dypsis lutescens and Caryota urens were used to prepare ethanolic and aqueous extract. Diabetes was induced by streptozotocin injection Intra peritoneally (i.p) in all experimental animals groups except normal control group. Group I (normal control) rats received distilled water and Group II to Group VII animals treated with streptozotocin to induce diabetes and titled diabetic rats. Group III rats were treated with glibenclamide and served as standard group, whereas Group IV to VII rats were treated with leaves extract of Dypsis lutescens and Caryota urens respectively. Physical parameters (Feed Intake, Body Weight), Biochemical parameters (Blood Glucose, Liver Glycogen, Serum aamylase, Serum Insulin, Total cholesterol, TG, HDL and LDL level) were measured timely. The study results indicate that oral administration of leaves extracts of Dypsis lutescens has proven to be more effective and safe anti-diabetic agent in comparison to leaves extracts of Caryota urens. Keywords: Diabetes, Dypsis lutescens, Caryota Urens, Streptozotocin
Publication date: 25/09/2021

https://ijbpas.com/pdf/2021/September/MS_IJBPAS_2021_SEPT_SPCL_1014.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.9.1014