A REVIEW ON STATIN THERAPY FOR REDUCTION IN BLOOD PRESSURE Authors: Prakash R , SANDHIYA P AND SOMASUNDHRAM I*
ABSTRACT
Hypertension and hypercholesterolemia are two of the major risk factors for cardiovascular
events (CV) which usually coexist among 40- 60% patients. Data suggests that almost 47% of
patients with high cholesterol levels also have high blood pressure. Although antihypertensive
and cholesterol lowering drugs are effective separately, a combination of both is much
efficacious in reducing major CV events, as it increases compliance. Statin’s effect on
cardiovascular protection may be beyond just lipid lowering. Statins are known to have
pleiotropic effects, which may help in reducing BP along with cholesterol. A number of studies
focus on the blood pressure lowering effect of HMG CoA reductase inhibitor. Further studies are
need of the hour to better evaluate the benefits of statin therapy in such patients. A widespread
literature search was carried out from Pubmed, and articles relevant to the current topic were
selected.
Keywords: Hypertension, Hypercholesterolemia, Statin therapy, Cholesterol Publication date: 01/10/2021 https://ijbpas.com/pdf/2021/October/MS_IJBPAS_2021_5647.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2021/10.10.5647
