Vitis vinifera commonly called Grape is a deciduous woody climber with coiled climbing
tendrils and large leaves. It has small, pale, green flowers in the summer followed by bunches
of berry fruits that range from green to purple-black. The leaves of the plant, which have
astringent and hemostatic properties, are used in the treatment of diarrhea, hemorrhage,
varicose veins, hemorrhoids, an inflammatory disorder, pain, hepatitis, and free radical
related diseases. The objective of the study was to evaluate antidiabetic, antibacterial
activities, and GC-MS analysis of methanol Grape peel extract. The maximum ?-amylase
enzyme inhibition was 88.17±0.91% at 120 ?g/mL concentration and the IC50 was 14.33
?g/mL concentration. The antibacterial activity of Grape peel extract showed the zone of
inhibition of 22 mm against Staphylococcus aureus at 500 ?g/mL concentration. The GC-MS
analysis showed the presence of antibacterial compounds such as 14,17- Octadecadienoic
acid, methyl ester, Hexadecanoic acid methyl ester, 2-Acetyl-3,5,8-trihydroxy-6-methoxy-
1,4-Naphthoquinone in the methanol Grape peel extract.
Keywords: Vitis vinifera, antioxidant activity, DPPH, antibacterial, antidiabetic, GC-MS
Publication date: 01/10/2021
https://ijbpas.com/pdf/2021/October/MS_IJBPAS_2021_5643.pdf
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https://doi.org/10.31032/IJBPAS/2021/10.10.5643
