ABSTRACT

First row transition metal complexes of Cr(III) & Mn(II) with bidentate schiff base have been synthesized and characterized by spectral, analytical and biological characterization. Molecular formula and metal ligand ratio of metal complexes illustrated by analytical data (elemental analysis and metal estimation), the binuclear and octahedral geometry around the Cr(III) and Mn(II) ions were predict base on the results of magnetic moment and ultraviolet visible spectral method. Based on the results of stretching frequencies of functional group present in the metal chelates were confirmed by IR and Far-IR spectral studies. In-vitro biological activities of schiff base and its metal complexes were predicted and compared with the standards (bacterial and fungal) using the strain viz., E.coli & A. niger. The complexes show enhanced bio-potential activities than the schiff base. In-vitro antioxidant activity of Cr(III) and Mn(II) complexes was carried out free radical DPPH scavenging method. The IC50 values show the complexes are higher antioxidant activities. Keywords: schiff base, spectral studies, octahedral, Bio-potential activity, scavenging activity, Antioxidant
Publication date: 01/10/2021

https://ijbpas.com/pdf/2021/October/MS_IJBPAS_2021_5640.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.10.5640