ABSTRACT

Background: The compounds which are present in plants and obtained by primary or secondary metabolism are known as phytochemicals. These phytochemicals act either as a drug or as a source for preparation of drugs Capsicum contains many useful phytochemicals such as flavonoids, carotenoids and phenolics and claimed to be responsible for antioxidant activity. This property of capsicum can protect the body from free radicals and oxidation process. The present study was aimed to perform a comparative phytochemical and pharmacological study with focus on analgesic activity using mouse models. Materials and Methods: Three different capsicum varieties such as green chilli, red chilli and capsicum (Capsicum annum belongs to the family Solanaceae) were grinded into coarse particles using mechanical grinder and subjected to methanolic extraction. Results and Discussion: Percentage yield of methanolic extract of 3 different varieties such as green chilli, red chilli and capsicum was found to be 8.9, 17.8, and 10% w/w respectively. These methanolic extracts were further subjected to phytochemical screening. Conclusion: This study results revealed that all three varieties of capsicum (green chili, red chili and capsicum) possess similar phytochemicals such as carbohydrates, alkaloids and tannins. These phytochemicals could be responsible for various pharmacological activities including analgesic activity of capsicum varieties. Keywords: Phytochemicals, Flavanoids, Free Radicals, Carotenoids, Phenolics, Solanaceae, Phytochemical screening, Mechanical Grinder
Publication date: 01/10/2021

https://ijbpas.com/pdf/2021/October/MS_IJBPAS_2021_5380.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.10.5380