ABSTRACT

Aim: Preparation of lycopene, raspberry, green tea and silver nano particle herbal formulation and assessing its cytotoxicity. Materials and methods: Extracts of 25% raspberry, 10% lycopene, green tea (95% of polyphenols) and silver nanoparticles are subjected for Herbal formulation preparation, and is subjected to cytotoxicity testing, the formulation was prepared using carboxymethylcellulose, hydroxypropyl methyl cellulose, Carbopol, sodium chloride, and distilled water, Toxicity testing using brine shrimp lethality assay. Results: The maximum survival rate of brine shrimp at the highest dose of 80?l is 7 (out of 10) and at least concentration of 5?l all the 10 shrimp fishes survived in 24 hrs.Conclusion:the combination of lycopene, raspberry, green tea and silver nanoparticles have shown the least cytotoxic effect at various concentrations of herbal extracts. Keywords: Lycopene, nanoparticle, cytotoxicity
Publication date: 01/09/2021

https://ijbpas.com/pdf/2021/September/MS_IJBPAS_2021_6212.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.9.6212