ABSTRACT

A polyherbal formulation was designed for alcohol use disorders and an experimental validation of the same was carried out for its hepatoprotective activity against ethanol and paracetamol induced liver damage in swiss albino rats. The rats were divided into four groups of ten animals each with two study groups, one toxic control group and one normal control group. The polyherbal formulation was coded as Sumukti and was prepared in syrup form by combination of 11 drugs. The study groups were fed with Sumukti syrup for 21 days and 31 days respectively along with hepaotoxic drugs like ethanol and paracetamol. Biochemical parameters like Liver function test Histopathological studies of liver cells were carried out. Results were suggestive of hepatoprotective activity of study formulation. Keywords: Sumukti syrup, polyherbal, Hepatoprotective, indigenous
Publication date: 01/09/2021

https://ijbpas.com/pdf/2021/September/MS_IJBPAS_2021_5634.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.9.5634