ABSTRACT

The aim of present study was to develop a polyherbal solid dosage formulation using Phyllanthus emblica (Amla) and Rauwolfia serpentina (Indian snakeroot) in defined ratio. Polyherbal formulation was developed using powders of medicinal plant parts like Amla fruit and Rauwolfia root. These powders were evaluated for their physical properties like Bulk density, tapped density, Angle of repose and Hausner’s ratio separately. Granules were prepared using wet granulation technique with the help of powders and other excipients. Polyherbal tablets were formulated finally and evaluated by different methods like Physical appearance, Thickness, Weight variation, Hardness, Friability and Disintegration and all were within the acceptance limits. Optimized formulation F5 can be used for treating hypertension with less side effects and maximum potency rate. Keywords: Amla, Rauwolfia, polyherbal tablets, wet granulation
Publication date: 01/09/2021

https://ijbpas.com/pdf/2021/September/MS_IJBPAS_2021_5632.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.9.5632