ESTIMATION OF ALLOPURINOL – A REVIEW Authors: Ch Jaswanth Kumar , KAMAKSHI DEVI N, PRACHET P, SAI TEJASWI A AND RAMA RAO N
ABSTRACT
The present review article focuses on the estimation of Allopurinol and its combination of
drugs by various analytical techniques. Allopurinol is used in the treatment of Gout and it
acts by decreasing the uric acid levels in the blood. Allopurinol and a combination of a few
drugs like flucytosine, ?-lipoic acid, febuxostat, benzbromarone, oxypurinol, lesinuradare
reviewed in this article. Estimation of the above-mentioned drugs by using various analytical
tools like UV-Vis spectrophotometer, Ultra Performance Liquid Chromatography (UPLC),
Liquid chromatography- Tandem mass spectrophotometry (LC-TMS), Hydrophilic- Liquid
Interaction Chromatography (HILIC), High-Performance Liquid Chromatography (HPLC).
Key words: Allopurinol, Febuxostat, Benzbromarone, Chromatography, Hyperuricemia Publication date: 01/09/2021 https://ijbpas.com/pdf/2021/September/MS_IJBPAS_2021_5608.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2021/10.9.5608