ABSTRACT

Herbal products are of interest to many patients and health care practitioners as about 70% of population worldwide rely on herbal medicines for part of their primary health care. When herbs are used in combination, the effects can be complicated as various interactions can occur among the individual components. The most desirable interactions are those which can result in additional therapeutic benefit. Aim: The present study aims at investigating the antioxidant and antimicrobial potentials of herbal combination of Rosemary and Mint extracts. This study is done to investigate the relationship between total phenolic content, antioxidant activity and antimicrobial properties of different herbal combinations. Materials & Methods: The antioxidant activities were determined by in vitro assays to compare their antioxidant effects. These include DPPH (1,1-diphenyl-2- picrylhydrazyl) assay, FRAP (Ferric reducing antioxidant power) assay, ABTS (2,2’-azino-bis-3- ethylbenzthiazoline-6-sulphonic acid) assay, TFC (total flavonoid content) determination and TPC (total phenolic content) determination. The antibacterial effects of various herbal combinations of Rosemary and Mint extracts against infectious bacterial strains were also evaluated. Results: Our results demonstrated the antioxidant potential of herbal combination of hydroalcoholic extract of Rosmary:Mint::70:30 was highest and Rosemary:Mint::10:90 was lowest. Similarly antibacterial effect was maximally exhibited by Rosemary:Mint::70:30 combination and minimally exhibited by Rosemary:Mint::10:90 using two Gram positive and Gram negative strains. Our resultssuggest that hydroalcoholic extracts of Rosemary:Mint in the ratio of 70:30 has highest antioxidant potential and antibacterial property. Hence this combination is best suited for further analysis. Keywords: Rosemary, Mint, Antioxidant, antimicrobial, hydroalcoholic extract, FRAP, DPPH
Publication date: 01/09/2021

https://ijbpas.com/pdf/2021/September/MS_IJBPAS_2021_5607.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.9.5607