ABSTRACT

India has today become the diabetic capital of the world with over 20 million diabetes and this number is likely to increase to 57 million by 2025. Diabetes is caused by metabolic disorder of the body systems as a result of chronic hyperglycaemia. Diabetes mellitus is a systemic metabolic disease characterized by hyperglycemia, hyperlipedemia, hyperaminoacidemia, and hypoinsulinaemia it leads to decrease in insulin, secretion and insulin action. Currently available therapies for diabetes include insulin and various oral antidiabetic agents such as sulfonylureas, biguanides, ?-glucosidase inhibitors and glinides. In developing countries products are expensive and not easily accessible. The World Health Organization (WHO) has listed 21,000 plants, which are used for medicinal purposes around the world. A list of medicinal plants with proven antidiabetic and related beneficial effects and of herbal drugs used in treatment of diabetes is compiled. Hibiscus rosa?sinensis, Gossypium herbaceum, Abutilon indicum are ethnomedicinal plants of Malvaceae family commonly used Indian traditional system of medicines. Traditionally these plants were used in the form of extract/powder/paste by tribal populations of India for treating common ailments like cough and cold, fever, kidney, liver disorders, pains, inflammations, wounds etc. The present review is an overview of phytochemistry and ethnopharmacological studies that support many of traditional ethnomedicinal uses of these plants. Many phytoconstituents have been isolated from the three ethnomedicinal plants andsome of them have shown pharmacological activities that have been demonstrated by in vivo/invitro experiments. Ethnomedicinal uses, supported by scientific evidences are essential for ensuring safe and effective utilization of herbal medicines. Keywords: Hibiscus rosa sinensis; Gossypum herbaceum; Abutilon indicum; ethnopharmacological; Malvaceae; phytoconstituents
Publication date: 01/08/21

https://ijbpas.com/pdf/2021/August/MS_IJBPAS_2021_5591.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.8.5591