ABSTRACT

The main aim of this review is to provide a brief overview of analytical methods like spectrophotometric and chromatographic methods for the analysis of Raltegravir in pharmaceuticals to researchers. Integrase inhibitors, also called as integrase strand transfer inhibitor (INSTI) are one of the class of antiretroviral (HIV) drugs intended to block integrase action. Integrase is a viral enzyme that inserts viral genome into DNA of host cell. Integration is an important step in retroviral replication, blocking of integrase enzyme can halt further spread of virus. Various analytical methods for Raltegravir are reviewed in this article along with their experimental conditions in bulk, pharmaceutical dosage forms. Keywords: Raltegravir, spectrophotometric, chromatographic, HIV, analytical methods
Publication date: 01/08/21

https://ijbpas.com/pdf/2021/August/MS_IJBPAS_2021_5573.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.8.5573