ABSTRACT

Amelogenesis imperfecta represents a heterogeneous group of inherited disorders characterized by very thin dental enamel. Defects in mineralization or matrix formation during tooth development lead to enamel hypoplasia and/or hypo mineralization. Mutations in several toothspecific genes are associated with the disease. In this study we desired to study the ameloblastin protein at different levels of protein structure. The functional and structural role of ameloblastin is not clearly understood. We found a possible kinase phosphorylation site based on signal at position 27. Therefore, this study would help us to gain deeper insights into the same using insilico approaches. Keywords: Bioinformatics Profiling, Salivary Ameloblastin, abnormal enamel
Publication date: 01/08/21

https://ijbpas.com/pdf/2021/August/MS_IJBPAS_2021_5559.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.8.5559