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SYNTHESIS OF PYRAZOLINES (substituted 4,5-dihydro-5-(2-methoxynaphthalen-6- yl)-1H-pyrazol-3-yl)(phenyl) USING ALUM [KAl (SO4)2.12H2O] AS AN EFFICIENT AND NOVEL CATALYST AND THEIR MICROBIOLOGICAL ACTIVITY
Authors: Ansar R. Shaikh , MAZAHAR FAROOQI, CHISTY S.Q., SYED ABED, SHAIKH SIRAJ N

ABSTRACT
Herein we report, Synthesis of Pyrazolines using alum as a novel catalyst. Alum [KAl (SO4)2·12H2O] performs as a novel catalyst for the synthesis of Pyrazolines from various substituted Chalcones [various substituted (E)-3-(2-methoxynaphthalen -6-yl)-1-phenylprop- 2-en-1-one)] in good to excellent isolated yield (60–76%) using ethanol as a solvent for reaction. The remarkable advantages offered by this method is an inexpensive and easily available catalyst, a simple procedure, mild reaction conditions and faster the reactions. The structures of synthesized compounds elucidated using IR Spectroscopy, Mass Spectrometry, 1H NMR Spectroscopy and 13C Spectroscopy. Keywords: Pyrazolines, Alum, Substituted Chalcones, Microbiological activity
Publication date: 01/07/21
    https://ijbpas.com/pdf/2021/July/MS_IJBPAS_2021_5587.pdf
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https://doi.org/10.31032/IJBPAS/2021/10.7.5587

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