ANALYTICAL METHODS OF SAXAGLIPTIN A DPP-4 INHIBITOR: A REVIEW Authors: Pathak S And Bansal K*
ABSTRACT
Saxagliptin is dipeptidyl peptidase protein-4 and active renal glucose reabsorption inhibitors. It is
used in type 2 diabetes patients. They are administered as tablets. It has numerous analytical
papers for Reverse Phase-High Performance Liquid Chromatography and Ultraviolet
Spectroscopy estimation of the Active Pharmaceutical Ingredient or drug formulation. The use of
chemical, drug and solvent separation methods used for green chemistry in pharmaceutical
products is very difficult. Phosphate buffer and other toxic reagents were mainly used for
estimation in this analysis and these agents damage tools as well as the environment and a lot of
waste, so that novel analytical techniques for quantifying and identifying Saxagliptin should be
developed for the person and the community as easily and safely as possible. This review focuses
on the essential physicochemical state, properties, intervention, and aims to concentrate on
various analytical methods for Saxagliptin estimation in pharmaceutical formulation.
Keywords: Saxagliptin, RP-HPLC methods, UV methods, Pharmacokinetic Publication date: 01/07/21 https://ijbpas.com/pdf/2021/July/MS_IJBPAS_2021_5551.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2021/10.7.5551
