PHARMACEUTICAL INDUSTRY EFFLUENT AS A VIABLE SUBSTRATE FOR POLYHYDROXYALKANOATE (PHA) PRODUCTION Authors: Saxena NK , TYAGI P AND SHARMA A
ABSTRACT
Polyhydroxyalkanoates (PHAs) are microbial biopolymer that are accumulated in various
microorganisms during nutrient deficient conditions. PHA possesses various characteristics
like biodegradability, biocompatibility, high tensile strength and non-toxicity - which make it
a suitable replacement for synthetic plastics. The high production cost of
Polyhydroxyalkanoate is the key factor that hinders the commercialization of this
biopolymer. In the current study, pharmaceutical industry effluent (PHI) has been used as a
substrate and the conditions were standardized to maximize the yield of PHA and in process
reducing the cost of PHA production. Maximum PHA yield was obtained at pH of 7.5 with
peptone at a concentration of 30% PHI. Thus, this study demonstrates the utilization of
pharmaceutical industrial effluent as a substrate for PHA production. This allows potential
reduction in cost of the PHA production process while also bioremediating the industrial
effluent; promoting sustainable development.
Keywords: Polyhydroxyalkanoates, Biodegradable, pharmaceutical industrial effluent,
Media optimization Publication date: 01/06/21 https://ijbpas.com/pdf/2021/June/MS_IJBPAS_2021_5532.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2021/10.6.5532