PHARMACEUTICAL INDUSTRY EFFLUENT AS A VIABLE SUBSTRATE FOR POLYHYDROXYALKANOATE (PHA) PRODUCTION
Authors: Saxena NK , TYAGI P AND SHARMA A

ABSTRACT
Polyhydroxyalkanoates (PHAs) are microbial biopolymer that are accumulated in various microorganisms during nutrient deficient conditions. PHA possesses various characteristics like biodegradability, biocompatibility, high tensile strength and non-toxicity - which make it a suitable replacement for synthetic plastics. The high production cost of Polyhydroxyalkanoate is the key factor that hinders the commercialization of this biopolymer. In the current study, pharmaceutical industry effluent (PHI) has been used as a substrate and the conditions were standardized to maximize the yield of PHA and in process reducing the cost of PHA production. Maximum PHA yield was obtained at pH of 7.5 with peptone at a concentration of 30% PHI. Thus, this study demonstrates the utilization of pharmaceutical industrial effluent as a substrate for PHA production. This allows potential reduction in cost of the PHA production process while also bioremediating the industrial effluent; promoting sustainable development. Keywords: Polyhydroxyalkanoates, Biodegradable, pharmaceutical industrial effluent, Media optimization
Publication date: 01/06/21
    https://ijbpas.com/pdf/2021/June/MS_IJBPAS_2021_5532.pdf
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https://doi.org/10.31032/IJBPAS/2021/10.6.5532