ABSTRACT

Panchkol churna is a polyherbal traditional preparation in India. The medicinal plants, used in this preparation are Piper longum Linn. (Pippali), Piper chaba Huntur/Piper retrofractum.Vahl. (Chavya), Plumbago zeylanica Linn. (Chitraka), Zingiber officinale Roscoe (Shunti/Nagara). This formulation is traditionally recommended for various diseases like an abdominal tumor, abdominal pain, loss of appetite, GI disorder, cold, cough, etc. In this study, the polyherbal preparation Panchkola churna and it's extract was prepared and given orally to Wistar albino rats to evaluate anti-inflammatory activity. This study carried out to investigate the anti-inflammatory activity of Panchkola churna at a dose 500mg/kg, 750 mg/kg, 1000mg/kg p.o and extract 20 mg/kg, 30 mg/kg and 40 mg/kg b.w. p.o in experimental rat models. The study was done in selected two models that are Egg-albumin induced rat paw edema and cotton pellet induced rat paw edema model. Both Panchkola churna and hydroalcoholic extract showed significant activity against inflammation in both models. Keywords: Churna, Pippali, Edema, Egg Albumin, Granuloma, NSAID
Publication date: 01/06/21

https://ijbpas.com/pdf/2021/June/MS_IJBPAS_2021_5526.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.6.5526