ABSTRACT

Objective: The aim of the study is discussing briefly about the review on preparation, characterization of solid lipid nanoparticles and its future application. Discussion: Solid lipid nanoparticles are most developing formulations of nanotechnology with few applications in various fields like drug delivery, clinical medicine, cosmetics, and research even in other varied sciences. Nowadays researchers are focused on solid lipid carriers as colloidal drug carrier systems. Indeed, the solubility and bioavailability of poorly soluble drugs can be enhanced and utilizing diverse biodegradable and bio acceptable polymers helps to overcome the harmful impact of traditional drug carrier system. Conclusion: This review focuses mainly on various approaches in industrial scale-up techniques of solid lipid nanoparticles with its merits and demerits, production methodology, and applications. The characterization of solid lipid nanoparticles is usually using different analytical techniques like photon correlation spectroscopy, scanning microscopy, differential scanning calorimetry, etc. Simultaneously, this review underlines on recent research trends concerning to this carrier system. Keywords: Solid lipid nanoparticles, solid lipid, surfactants, biocompatibility, drug delivery
Publication date: 01/06/21

https://ijbpas.com/pdf/2021/June/MS_IJBPAS_2021_5523.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.6.5523