ABSTRACT

Dendrimers are highly branched molecules having a well-defined size, shape, molecular weight, and monodispersity as compared to a linear polymer. Dendrimer has a tree-like shape, consist of central core, branches and terminal group. The bioactive agents may either be encapsulated into the interior of the dendrimers or they may be chemically attached or physically adsorbed onto the dendrimer surface. Dendrimer has wide application in the pharmaceutical field, in gene transfection, as a diagnostic agent, as a blood substituent, as a solubility enhancer. Surface-modified dendrimers themselves may act as nano-drugs against tumours, bacteria, and viruses. This review focus on structure, property, method of synthesis, various method of characterization, application and formulation of dendrimers. Key words: Dendrimers; Convergent; Divergent; applications; synthesis
Publication date: 01/06/21

https://ijbpas.com/pdf/2021/June/MS_IJBPAS_2021_5484.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.6.5484