PHYTOCHEMICALS IN TREATMENT OF OBESITY Authors: Nafeesa S* And Anjana M
ABSTRACT
Obesity is an increase in body weight because of excess body fat. It is difficult to directly
measure body fat, Body Mass Index (BMI) is popular method of defining a healthy weight. BMI
is a measure for human body shape based on an individual’s mass and height. BMI is Weight
(kg) divided by Height (m) 2. Obesity is commonly found to be associated with metabolic
disorders such as Diabetics, Hypertension, Cardiovascular diseases. The main causal factor for
obesity is hypo - caloric diets (decreased energy intake) and increased physical activity
(increased energy output). Pathogenesis of obesity involves two related but distinct processes: 1)
Sustained Positive Energy Balance (energy intake > energy expenditure) and 2) Resetting of the
body weight “Set Point” at an increased value. Phytochemicals are chemicals of Plant origin.
Phytochemicals (from Greek Phyto, meaning “Plant”) are chemicals produced by plants through
primary or secondary metabolism. Phytochemicals have been used as poison and in traditional
medicine. For e.g. The tropane alkaloids of A.belladonna were used as poisons, and early
humans made poisonous arrows from the plant. Phytochemicals are secondary metabolites of
which there are several classes including alkaloids, flavonoids, coumarins, glycosides, gums,
Polysaccharides, Coumarins, glycosides, polysaccharides, Phenols, tannins, terpenes and
terpenoids. Phytochemicals are used as potential agents in treatment of obesity. The compounds
of phytochemicals have biological properties such as antioxidant, modulation of detoxification enzymes, stimulation of immune system. This review aims to elucidate the beneficial role for
treatment of obesity in case of phytochemicals.
Keywords: Obesity, Pathogenesis, Phytochemicals, Causes, Symptoms Publication date: 01/04/21 https://ijbpas.com/pdf/2021/April/MS_IJBPAS_2021_5359.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2021/10.4.5359