ABSTRACT

Non alcoholic fatty liver disease is the most common health burden in developed countries. The spectrum of liver damage includes NASH, advanced fibrosis and rarely progresses to cirrhosis. Insulin resistance, oxidative stress, lipid peroxidation, mitochondrial dysfunction play a major role in the development of NAFLD. Our study strongly suggest that the association of non alcoholic fatty liver disease as a possible component in metobolic syndrome. This cross sectional study was conducted in Vazhudavur, Pondicherry from Nov 2018- Jan 2019. 1000 people participated in this study whose age was 30 and above. Anthropometry measurements, random blood sugar, blood pressure measurements, BMI, and USG were evaluated to screen for metabolic syndrome. A questionnaire was used to obtain information regarding history and quantity of alcohol consumption. Metabolic syndrome was defined in all participants based on national cholesterol education program adult treatment panel lll (2001) (NCEP/ATP lll) for clinical diagnosis of metabolic syndrome. Non alcoholic fatty liver disease was detected in 33.1% and 27.4% of men and women respectively. NAFLD is mainly associated with the development of MetS. However, it was not possible to determine whether NAFLD preceded the development of MetS. Keywords: Non-alcoholic fatty liver disease, Metabolic syndrome, NCEP/ATP-III, Waist circumference, Hyperglycemia
Publication date: 1/1/21

https://ijbpas.com/pdf/2021/January/MS_IJBPAS_2021_JAN_SPCL_1009.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.1.1009