BIOCHEMICAL INVESTIGATIONS IN GASTRIC CANCER PATIENTS Authors: T.Mohanalakshmi , MAHADEO MANE, KANAGATHARA.N, ASAYAS BOSCO CHANDRA KUMAR, E.PRABHAKAR REDDY*
ABSTRACT
Gastric cancer is one of the most common malignant diseases with one of the highest
mortality rates worldwide. Over 95% of gastric cancer cases are adenocarcinomas. The study
aim is to detection of Tumor Markers and other Biochemical investigations in the serum. 60
gastric cancer patients, 36 were male and 24 were female aged 43-65 years and 100 health
control group, 50 males and 50 females aged 44-64 years were included in this study.
Increased Total cholesterol, triglycerides, alkaline phosphatase, creatinine, uric acid, BUN
(Blood Urea Nitrogen ), CK-MB, LDH levels were found and decreased HDL levels were
found in patients with gastric cancer when compared with healthy controls. The combined
detection in the blood biochemical investigations and tumor markers is of important reference
value for screening of patients with gastric cancer and can provide the basis for early treatment of the disease. With a larger trial, we would be able to make more definitive
statements regarding the importance of these biochemical parameters and the proper timing
for measurement.
Keywords: Adenocarcinoma, Tumor Markers, Helicobacter pylori, Carcinoma
Embryionic Antigen Publication date: 1/1/21 https://ijbpas.com/pdf/2021/January/MS_IJBPAS_2021_JAN_SPCL_1005.pdfDownload PDFhttps://doi.org/10.31032/IJBPAS/2021/10.1.1005