ABSTRACT

CRF refers to an irreversible decay of renal capacity, which traditionally creates over a time of years. At first, it is show just as a biochemical irregularity. In the long run loss of excretory, metabolic and endocrine elements of the kidneys prompts the improvement of the clinical side effects and indications of renal disappointment, which are alluded to as uremia. The aim of our study is comparison Endothelial Dysfunction Marker and CVD Marker in CRF, HD (Pre &Post) and Controls. The present study was conducted on a patient group comprising of 50 patients diagnosed with CRF, 50 were pre hemodialysis, 50 were post hemodialysis (MHD). This patient group was compared to a healthy group including 100 controls. All the study participants were admitted in the department of Medicine [Nephrology department] at “Fathima Institute of Medical Sciences”, Kadapa. Andhra Pradesh. India. The obtained serum samples were used for biochemical analysis for estimating nitric acid and homocystine. Cardiovascular diseases are common in patients with CKD, and CKD is a major risk factor for CV diseases. In our study increased nitric acid levels were seen in pre HD, Post HD and CRF patients. In our study increased Hcy levels were seen in pre HD, Post HD patients. Keywords: Nitric acid, Homocystine, CVD, chronic kidney disease, Endothelial Dysfunction
Publication date: 1/1/21

https://ijbpas.com/pdf/2021/January/MS_IJBPAS_2021_JAN_SPCL_1001.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.1.1001