ABSTRACT

Transdermal drug delivery system is one of the system in the controlled drug delivery category, which aim was to delivered the drug at pre-determined and controlled rate through the skin. TDDS is a painless method of delivering drugs systemically by applying onto healthy skin. So TDDS is an important delivery route that transfer precise amount of drug through the skin for systemic action. Several important advantages of TDDS: continuous input of drug with short biological half-lives, enhancement of therapeutic efficiency and maintenance of steady plasma level of the drug delivery route that transfer precise amount of drug through the skin for systemic action. Transdermal drug delivery system also known as “patches” are dosage form in which transfer of the drug through skin for local therapeutically effect. Evaluation of transdermal patches is use to check its thickness, moisture content, drug content, time of onset, time of duration, weight of patches, quality of patches, size, adhesive property and toxicological studies. This review article provides an overview of TDDS, advantages, disadvantages, limitation, components of transdermal patches, various methods of preparation of TDDS and evaluation of transdermal patches. Keywords: TDDS, controlled rate, transdermal patch, controlled drug delivery system
Publication date: 01/02/21

https://ijbpas.com/pdf/2021/February/MS_IJBPAS_2021_5364.pdf

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https://doi.org/10.31032/IJBPAS/2021/10.2.5364