ABSTRACT

Background: Earlier studies have suggested that every year stroke kills more women than men. As per American stroke association and CDC’S national center for health statistics, stroke causes almost double the number of fatalities than fatalities caused by breast cancer. According to the American heart association, in 2017, there were 84,738 women fatalities due to the stroke which constituted 57.9% of all fatalities caused by stroke in USA. Methods: We collected relevant information from one thousand two hundred fourteen female control subjects (selected randomly) and 772 female ischemic stroke patients (IS). We also collected blood test results from 213 patients who were hospitalized for brain hemorrhage (HS). Additionally,we also collected total lipid profile and the blood test results from 307 female hypercholesterolemia (HC) patients who were admitted to King Suleiman hospital in Hail SA. Patient data was collected only from patient files by fifth year male and female medical students and the medical interns. Results: Since our sample size was large, we used Z test to calculate statistical significance of blood antigen distribution frequencies between controls and HS and HC female patients. Results of statistical analysis show a significantly reduced expression of “A” and “AB” antigens in HS female patients in comparison to the control female subjects. In contrast we saw significant rise in “B” antigen distribution in HS female patients as compared to the controls. Likewise, there was a high prevalence of hypercholesterolemia in B+patients. Conclusions: Our results suggest a correlation between blood group distribution, hypercholesterolemia and HS diseases. B blood type shows a significantly higher distribution in HS and hypercholesterolemia female patients as compared tocontrols. Keywords: Cholesterol, Diabetes, Obesity, Stroke Abbreviations: AHA: American Heart Association; CHD: Coronary heart disease; HDL: High density lipoproteins; HS: Hemorrhagic stroke; HC: Hypercholesterolemia; IS: Ischemic stroke; LDL-C: LDL Cholesterol; TGs: Triglycerides; TS: Transient stroke.
Publication date: 1/1/21

https://ijbpas.com/pdf/2021/January/MS_IJBPAS_2021_5654.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2021/10.1.5654