ABSTRACT

Introduction Conventional suture materials tend to accumulate microorganisms which be the possible cause of surgical wound infection. This led to the use of tissue adhesives like cyanoacrylate. The aim of this study is to assess if iso-amyl cyanoacrylate tissue adhesive had an inherent antimicrobial effect. Material and Methods Pure cultures Staphylococcus Aureus, Lactobacillus, Pseudomonas Aeruginosa and Candida Albicans were seeded on agar plates with different volumes of iso-amyl cyanoacrylate or n-butyl cyanoacrylate were prepared. Ampicillin and amphotericin B were used as positive controls. The plates were incubated overnight at 37 o C and the zone of inhibition was measured. Results Cyanoacrylate exhibited an inhibitory activity against the gram positive organisms and candida but did not show any effect on the gram negative organism. The n-butyl cyanoacrylates exhibited stronger antimicrobial properties when compared to iso-amyl cyanoacrylate Keywords: Cyanoacrylate, tissue adhesive, antimicrobial, antibacterial
Publication date: 1/1/21

https://ijbpas.com/pdf/2021/January/MS_IJBPAS_2021_5299.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2021/10.1.5299