ABSTRACT

Objective: The present study was conducted to observe the behavior of the MI evaluating various cardiac biomarkers for the detection of MI in relation with Risk factors of hypertension in both genders, with or without Myocardial Infarction. Study Design: This case control study was conducted over indoor patients in Kashmir Institute of Cardiology Mirpur, Azad Jammu and Kashmir Pakistan. Materials and Methods: Study was conducted in Kashmir Institute of Cardiology Mirpur, Azad Jammu and Kashmir. Total 240 patients were recruited in the study. 120 admitted patients of Acute Myocardial Infarction (AMI) in Kashmir Institute of Cardiology were registered. The span of study was from June 2013 to July 2014. 120 age and sex matched controls were included in the study. Informed written consent was obtained by the participants of study. Detailed medical/surgical history was obtained and recorded. Results: The mean concentration of cardiac biomarkers, CK-NAC, CK-MB and LDH enzymes was analyzed in MI affected hypertensive and normotensive group of population. Conclusion: According to our findings, there was significant increase in cardiac enzymes CK-NAC, CK-MB and LDH in MI patients from both genders but there was an insignificant difference in non MI patients with hypertension. There is no evidence to support the later findings as reported earlier. Further analysis and study is needed to find the reasons for above-mentioned results in non-MI patients. Keywords: CK-NAC, LDH, Cardiac Enzymes in hypertensive, Myocardial infarction in hypertensive
Publication date: 01/12/2020

https://ijbpas.com/pdf/2020/December/MS_IJBPAS_2020_5320.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.12.5320