EVALUATION OF OXIDATIVE STRESS AND ANTIOXIDANT MARKERS DURING VARIOUS STAGES OF LACTATION IN SMALL RUMINANTS
Authors: Naeem M , KANWAL S, REHMAN ZU

ABSTRACT
The present study was conducted to evaluate the effect of oxidative stress through various antioxidative/oxidative systems during different lactation stages in sheep and goats. A total of 60 lactating ewes and does between 1.5 to 5 years age group comprised the experimental animals taken from Bahadar Nagar Farm, Okara. Thirty (30) female Lohi sheep and likewise 30 female Beetal goats were grouped into three different milking stages [lac I (n=10), lac II (n=10) and lac III (n=10)]. Blood samples were collected from the animals during three different lactation periods. Serum has been preserved at -20 0C and used for determination of Malondialdehyde (MDA), Superoxide Dismutase (SOD), Catalase (CAT), Ceruloplasmin (Cp), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT) and Gamma-glutamyl Transferase (GGT). Statistical analysis was done by two way ANOVA and Duncan Multiple Range Test (DMRT). MDA, SOD, CAT, Cp and GGT were significantly different (P?0.05) through various stages of lactation in sheep as well as in goats. Whereas, AST and ALT were not differ significantly during different stages of lactation in both the groups. In Conclusion, lactation may cause an increase in reactive oxygen species and antioxidant substances predicting that is very stressful for the animals. Keywords: Oxidants and antioxidants, Lactation, Liver Enzymes, Sheep, Goat
Publication date: 01/12/2020
    https://ijbpas.com/pdf/2020/December/MS_IJBPAS_2020_5314.pdf
Download PDF
https://doi.org/10.31032/IJBPAS/2020/9.12.5314