ABSTRACT

Cassia tora Linn. is a small shrub of significant medicinal importance. The fresh leaves and pods of this plant have been used as vegetable curry by tribal people in Amarkantak region, district Anuppur, Madhya Pradesh. The local tribal healers use the plant for mitigation of neurotoxicity and treatment of malaria. The present study was planned to identify the major phytochemicals of this plant and correlate them with reported pharmacological activity. The major components of methanol extract of fresh leaves of C. tora were identified by GCMS-NIST library. The details of major phytochemicals were searched and matched with available database on Pubchem. The pharmacological activities of the major components were searched from literature. 20 major compounds from the methanolic extract of C. tora leaves have been identified using GCMS-NIST library. The available data showed neuroprotective, antimalarial, antioxidant, anti-inflammatory, antimicrobial, antibacterial, antiviral, antiasthmatic, anticancer, antituberculosis, antirheumatic and cholesterol-lowering activities of the identified compounds. Laminitol, the most abundant phytoconstituent has been reported to possess antimalarial activity. The presence of major components with neuroprotective, anti-malarial, antioxidant activity as per literature, justifies the ethnopharmacological use of C. tora in this region. Keywords: Cassia tora, Methanol Extract, GCMS, Phytochemicals, Pharmacological activity
Publication date: 01/12/2020

https://ijbpas.com/pdf/2020/December/MS_IJBPAS_2020_5268.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.12.5268