ABSTRACT

PURPOSE The aim of the study was to compare the clinical efficacy of Dexamethasone with Ibuprofen to Ibuprofen alone on the postoperative sequelae of surgical removal of impacted third molars. MATERIALS AND METHODS: The present study was conducted on the 30 patients requiring surgical extraction of impacted third molars attending the Outpatient Department of Oral and Maxillofacial Surgery. The selected patients were randomly put on regimen 1 or regimen II in accordance with randomization plan. The measurements and recordings for pain and interincisal distance (mouth opening), were made on 1st, 3rd, and 7th day postoperatively on the scales designed for the purpose. The data recorded was compiled and put to statistical analysis. RESULTS It was observed from the present study that postoperative sequelae, that is, pain and trismus was significantly less in the regimen I group than regimen II group on the 1st and 3rd postoperative day. CONCLUSION The results of this study substantiate the fact that a single class of drugs (nonsteroidal antiinflammatory drug (NSAID)) is less effective in controlling postoperative inflammatory sequelae than the combination of ibuprofen (NSAID) and methylprednisolone (corticosteroid) following the third molar surgery. Therefore, this pharmaceutical combination should be considered for attenuation of postoperative sequelae in healthy patients undergoing surgical removal of impacted mandibular third molar. Keywords: Impacted third molars, comparative research, dexamethasone with ibuprofen, ibuprofen
Publication date: 01/11/2020

https://ijbpas.com/pdf/2020/November/MS_IJBPAS_2020_5276.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.11.5276