ABSTRACT

A nomogram is a graphical calculating device mainly used for the graphical computation of a mathematical function. It is basically a diagram consisting of scales representing the relationship between three or more variable quantities. The value of an unknown variable can be found by simple geometrical construction, by drawing a straight line intersecting the other scales at appropriate values. Oral Potentially Malignant Disorders (PMD) includes a variety of lesions and conditions characterised by an increased risk of malignant transformation to oral squamous cell carcinoma. A biopsy (histopathological examination) is considered to be the gold standard for the definitive diagnosis of an OPMD and its malignant progression. There are various chair side diagnostic aids like vital staining, light based detection systems and other non invasive diagnostic aids like exfoliative cytology like brush biopsy which can serve as adjuvants for diagnosis of these disorders and for proceeding with treatment planning such as need for biopsy for the definitive diagnosis. There are also various molecular and genetic markers which can be used in the diagnosis of OPMDs and oral cancer. This review highlights about various OPMDs, chair side diagnostic tools and aims to device a nomogram to predict the risk of malignant transformation of OPMDs using chair side diagnostic aids and histopathological examination. Key words: Nomogram, OPMDs, risk, malignancy
Publication date: 01/10/2020

https://ijbpas.com/pdf/2020/October/MS_IJBPAS_2020_5263.pdf

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https://doi.org/10.31032/IJBPAS/2020/9.10.5263