ABSTRACT

Cypermethrin used throughout the world in the agricultural fields and domestic purposes to control pests is known to have toxic potential to non-target aquatic organisms specially fishes. Poisoning leads to disturbance in the fish metabolism and other physiological process causing mortality in fishes. Flavonoids are the polyphenolic compounds present in green tea and garlic extract having various beneficial effects related to low toxicity in fishes. Besides several advantageous effects flavonoids also possess antioxidant property reducing oxidative damage caused by cypermethrin. The major polyphenols present in green tea are epicatechin, epigallocatechin, epicatechin-3-gallate and epigallocatechin-3-gallate (EGCG) in which EGCG is the most active component. Garlic consists of sulfur and non sulfur compounds like alliin, ajoene, diallyl polysulfides and S-allylcysteine in which the most active component of garlic is alliin (S-allyl cysteine sulfoxide) which is a potent antioxidant reducing non-target exposure of hazardous pesticides. The aim of this review is to demonstrate the adverse effects of cypermethrin in fishes and its mitigation by flavonoids (GTE and GE). Cypermethrin altered various biochemical parameters especially liver enzymes and kidney markers in fishes following exposure. The combination therapy i.e. cypermethrin along with GTE and GE combats cypermethrin toxicity. Keywords: Polyphenols, Green tea, Garlic, Cypermethrin, Fishes
Publication date: 01/10/2020

https://ijbpas.com/pdf/2020/October/MS_IJBPAS_2020_5211.pdf

Download PDF
https://doi.org/10.31032/IJBPAS/2020/9.10.5211